Dynamic full-field optical coherence tomography: 3D live-imaging of retinal organoids

  title={Dynamic full-field optical coherence tomography: 3D live-imaging of retinal organoids},
  author={Jules Scholler and Kassandra Groux and Olivier Goureau and Jos{\'e}-Alain Sahel and Mathias Fink and Sacha Reichman and Claude A. Boccara and Kate Grieve},
  journal={Light, Science \& Applications},
Optical coherence tomography offers astounding opportunities to image the complex structure of living tissue but lacks functional information. We present dynamic full-field optical coherence tomography as a technique to noninvasively image living human induced pluripotent stem cell-derived retinal organoids. Coloured images with an endogenous contrast linked to organelle motility are generated, with submicrometre spatial resolution and millisecond temporal resolution, creating a way to identify… 

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