Dynamic expression of two thrombospondins during axolotl limb regeneration.

@article{Whited2011DynamicEO,
  title={Dynamic expression of two thrombospondins during axolotl limb regeneration.},
  author={Jessica L. Whited and Jessica A Lehoczky and Christina A. Austin and Clifford J Tabin},
  journal={Developmental dynamics : an official publication of the American Association of Anatomists},
  year={2011},
  volume={240 5},
  pages={
          1249-58
        }
}
The molecular processes underlying regeneration remain largely unknown. Several potential factors have been elucidated by focusing on the regenerative function of genes originally identified in a developmental context. A complementary approach is to consider the roles of factors involved in wound healing. Here we focus on the Thrombospondins, a family of secreted extracellular matrix proteins that have been implicated in skin wound healing in mammals. We show that a subset of Thrombospondins… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-7 of 7 extracted citations

Inducible genetic system for the axolotl.

Proceedings of the National Academy of Sciences of the United States of America • 2012
View 2 Excerpts

References

Publications referenced by this paper.
Showing 1-10 of 27 references

The thrombospondins.

Cold Spring Harbor perspectives in biology • 2011
View 1 Excerpt

Skin wound healing in axolotls: a scarless process.

Journal of experimental zoology. Part B, Molecular and developmental evolution • 2010
View 2 Excerpts

Limb regeneration in higher vertebrates: developing a roadmap.

Anatomical record. Part B, New anatomist • 2005
View 1 Excerpt

Nitric oxide regulates angiogenesis through a functional switch involving thrombospondin-1.

Proceedings of the National Academy of Sciences of the United States of America • 2005
View 1 Excerpt

Thrombospondin-1 inhibits endothelial cell responses to nitric oxide in a cGMP-dependent manner.

Proceedings of the National Academy of Sciences of the United States of America • 2005
View 1 Excerpt