Dynamic expression of small non-coding RNAs, including novel microRNAs and piRNAs/21U-RNAs, during Caenorhabditis elegans development

@article{Kato2009DynamicEO,
  title={Dynamic expression of small non-coding RNAs, including novel microRNAs and piRNAs/21U-RNAs, during Caenorhabditis elegans development},
  author={Masaomi Kato and Alexandre de Lencastre and Zachary Pincus and Frank J. Slack},
  journal={Genome Biology},
  year={2009},
  volume={10},
  pages={R54 - R54}
}
Small non-coding RNAs, including microRNAs (miRNAs), serve an important role in controlling gene expression during development and disease. However, little detailed information exists concerning the relative expression patterns of small RNAs during development of animals such as Caenorhabditis elegans. We performed a deep analysis of small RNA expression in C. elegans using recent advances in sequencing technology, and found that a significant number of known miRNAs showed major changes in… CONTINUE READING
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