Dynamic evaluation of fluid shifts during normothermic and hypothermic cardiopulmonary bypass in piglets

@article{Heltne2000DynamicEO,
  title={Dynamic evaluation of fluid shifts during normothermic and hypothermic cardiopulmonary bypass in piglets},
  author={Jon Kenneth Heltne and M E Koller and T. Lund and Joel L. Bert and Stein Erik Rynning and Lodve B Stangeland and Paul Husby},
  journal={Acta Anaesthesiologica Scandinavica},
  year={2000},
  volume={44}
}
Background: Edema, generalized overhydration and organ dysfunction commonly occur in patients undergoing open‐heart surgery using cardiopulmonary bypass (CPB) and induced hypothermia. Activation of inflammatory reactions induced by contact between blood and foreign surfaces are commonly held responsible for the disturbances of fluid balance (“capillary leak syndrome”). We used an online technique to determine fluid shifts between the intravascular and the interstitial space during normothermic… 
Studies on fluid extravasation related to induced hypothermia during cardiopulmonary bypass in piglets
TLDR
The aim of the present study was to characterize the distribution of the fluid given to maintain normovolemia and investigate the quantity and quality of the liquid extravasated during hypothermic compared to normothermic CPB.
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The purpose of this work is to improve the understanding of fluid pathophysiology and to explore the implications of the changes in determinants of transcapillary fluid exchange during CPB with and without hypothermia.
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This study assessed whether lowering of the mean arterial pressure and/or the central venous pressure could reduce fluid extravasation during normothermic and hypothermic CPB.
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Hemodilution During Cardiopulmonary Bypass Increases Cerebral Infarct Volume After Middle Cerebral Artery Occlusion in Rats
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In this experimental model of CPB with reversible MCAO-induced focal cerebral ischemia, hemodilution worsened neurological function and increased cerebral infarct volume.
Comparison of Early Outcomes for Normothermic and Hypothermic Cardiopulmonary Bypass in Children Undergoing Congenital Heart Surgery
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