Dynamic developmental elaboration of N-linked glycan complexity in the Drosophila melanogaster embryo.

@article{Aoki2007DynamicDE,
  title={Dynamic developmental elaboration of N-linked glycan complexity in the Drosophila melanogaster embryo.},
  author={Kazuhiro Aoki and Mindy Perlman and Jae-min Lim and Rebecca Cantu and Lance Wells and Michael Tiemeyer},
  journal={The Journal of biological chemistry},
  year={2007},
  volume={282 12},
  pages={9127-42}
}
The structural diversity of glycoprotein N-linked oligosaccharides is determined by the expression and regulation of glycosyltransferase activities and by the availability of the appropriate acceptor/donor substrates. Cells in different tissues and in different developmental stages utilize these control points to manifest unique glycan expression patterns in response to their surroundings. The activity of a Toll-like receptor, called Tollo/Toll-8, induces a pattern of incompletely defined, but… CONTINUE READING