Dynamic control of the complement system by modulated expression of regulatory proteins

@article{Thurman2011DynamicCO,
  title={Dynamic control of the complement system by modulated expression of regulatory proteins},
  author={Joshua M Thurman and Brandon Renner},
  journal={Laboratory Investigation},
  year={2011},
  volume={91},
  pages={4-11}
}
The complement system serves many biological functions, including the eradication of invasive pathogens and the removal of damaged cells and immune-complexes. Uncontrolled complement activation causes injury to host cells, however, so adequate regulation of the system is essential. Control of the complement system is maintained by a group of cell surface and circulating proteins referred to as complement regulatory proteins. The expression of the cell surface complement regulatory proteins… CONTINUE READING
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