Corpus ID: 211677667

Dynamic contrast in scanning microscopic OCT

  title={Dynamic contrast in scanning microscopic OCT},
  author={Michael Munter and Malte vom Endt and Mario Pieper and Malte Casper and Martin Ahrens and Tabea Kohlfaerber and Ramtin Rahmanzadeh and Peter Konig and Gereon Huttmann and Hinnerk Schulz-Hildebrandt},
  journal={arXiv: Medical Physics},
  • Michael Munter, Malte vom Endt, +7 authors Hinnerk Schulz-Hildebrandt
  • Published 2020
  • Mathematics, Physics, Engineering
  • arXiv: Medical Physics
  • While optical coherence tomography (OCT) provides a resolution down to 1 micrometer it has difficulties to visualize cellular structures due to a lack of scattering contrast. By evaluating signal fluctuations, a significant contrast enhancement was demonstrated using time-domain full-field OCT (FF-OCT), which makes cellular and subcellular structures visible. The putative cause of the dynamic OCT signal is ATP-dependent motion of cellular structures in a sub-micrometer range, which provides… CONTINUE READING

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