Dynamic contrast-enhanced magnetic resonance imaging evaluation of VX2 carcinoma in a rabbit model: comparison of 1.0-M gadobutrol and 0.5-M gadopentetate dimeglumine.

@article{Chang2010DynamicCM,
  title={Dynamic contrast-enhanced magnetic resonance imaging evaluation of VX2 carcinoma in a rabbit model: comparison of 1.0-M gadobutrol and 0.5-M gadopentetate dimeglumine.},
  author={Jung Min Chang and Woo Kyung Moon and Joo Hee Cha and Eun-jung Jung and Nariya Cho and Seung Ja Kim},
  journal={Investigative radiology},
  year={2010},
  volume={45 10},
  pages={655-61}
}
OBJECTIVES To compare the enhancement characteristics and diagnostic performance of 1.0-M gadobutrol with those of 0.5-M gadopentetate dimeglumine in rabbit VX2 tumor models. MATERIALS AND METHODS Our study was approved by the Animal Care Committee of our hospital. VX2 carcinomas were implanted in both thighs of 14 rabbits 4 days before magnetic resonance (MR) imaging. The animals underwent 2 identical MR examinations with 2 different contrast media separated by 8 hours with the use of a 3.0… CONTINUE READING