Dynamic contrast-enhanced magnetic resonance imaging as a prognostic factor in predicting event-free and overall survival in pediatric patients with osteosarcoma.

@article{Guo2012DynamicCM,
  title={Dynamic contrast-enhanced magnetic resonance imaging as a prognostic factor in predicting event-free and overall survival in pediatric patients with osteosarcoma.},
  author={Junyu Guo and Wilburn E. Reddick and John O. Glass and Qing Ji and Catherine A. Billups and Jianrong Wu and Fredric A. Hoffer and Sue Creviston Kaste and Jesse J. Jenkins and Ximena C Ortega Flores and Juan Quintana and Milena Villarroel and Najat C. Daw},
  journal={Cancer},
  year={2012},
  volume={118 15},
  pages={3776-85}
}
BACKGROUND The objective of this study was to prospectively evaluate dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) as an early imaging indicator of tumor histologic response to preoperative chemotherapy and as a possible prognostic factor for event-free survival (EFS) and overall survival in pediatric patients with newly diagnosed, nonmetastatic osteosarcoma who were treated on a single, multi-institutional phase 2 trial. METHODS Three serial DCE-MRI examinations at week 0… CONTINUE READING

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