Dynamic contrast-enhanced MRI in head-and-neck cancer: the impact of region of interest selection on the intra- and interpatient variability of pharmacokinetic parameters.

Abstract

PURPOSE Dynamic contrast-enhanced (DCE) MRI-extracted parameters measure tumor microvascular physiology and are usually calculated from an intratumor region of interest (ROI). Optimal ROI delineation is not established. The valid clinical use of DCE-MRI requires that the variation for any given parameter measured within a tumor be less than that observed… (More)
DOI: 10.1016/j.ijrobp.2011.05.059

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Cite this paper

@article{Craciunescu2012DynamicCM, title={Dynamic contrast-enhanced MRI in head-and-neck cancer: the impact of region of interest selection on the intra- and interpatient variability of pharmacokinetic parameters.}, author={Oana I. Craciunescu and David S. Yoo and Esi Cleland and Naira Muradyan and Madeline D. Carroll and James R. MacFall and Daniel P. Barboriak and David M. Brizel}, journal={International journal of radiation oncology, biology, physics}, year={2012}, volume={82 3}, pages={e345-50} }