Dynamic conformational model for the role of ITS2 in pre-rRNA processing in yeast.

Abstract

Maturation of the large subunit rRNAs includes a series of cleavages that result in removal of the internal transcribed spacer (ITS2) that separates mature 5.8S and 25/28S rRNAs. Previous work demonstrated that formation of higher order secondary structure within the assembling pre-ribosomal particle is a prerequisite for accurate and efficient pre-rRNA… (More)

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Cite this paper

@article{Cote2002DynamicCM, title={Dynamic conformational model for the role of ITS2 in pre-rRNA processing in yeast.}, author={Colette A. Cote and Chris L Greer and Brenda A. Peculis}, journal={RNA}, year={2002}, volume={8 6}, pages={786-97} }