Dynamic chromatin boundaries delineate a latency control region of Epstein-Barr virus.

  title={Dynamic chromatin boundaries delineate a latency control region of Epstein-Barr virus.},
  author={Charles M Chau and Paul M. Lieberman},
  journal={Journal of virology},
  volume={78 22},
The oncogenic potential of latent Epstein-Barr virus (EBV) can be regulated by epigenetic factors controlling LMP1 and EBNA2 gene transcription. The EBV latency control region (LCR) constitutes approximately 12 kb of viral sequence spanning the divergent promoters of LMP1 and EBNA2 and encompasses the EBV latent replication origin OriP and RNA polymerase III-transcribed EBV-encoded RNA genes. We have used the chromatin immunoprecipitation assay to examine the chromatin architecture of the LCR… CONTINUE READING
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CHROMATIN DOMAIN IN THE EBV LCR 12317 on O cber 14, 2017 by gest http/jvi.asm .rg/ D ow nladed fom

  • Z. Deng, L. Lezina, C. J. Chen, S. Shtivelband, W. So, P. M. Lieberman
  • Mol. Cell 9:493–503
  • 2004
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