Dynamic changes of the luminal plasmalemma in stimulated parotid acinar cells. A freeze-fracture study

@article{Camilli1976DynamicCO,
  title={Dynamic changes of the luminal plasmalemma in stimulated parotid acinar cells. A freeze-fracture study},
  author={Pietro De Camilli and Dionisio Peluchetti and Jacopo Meldolesi},
  journal={The Journal of Cell Biology},
  year={1976},
  volume={70},
  pages={59 - 74}
}
In the acinar cells of the rat parotid gland the two membranes participating in exocytosis, i.e., the luminal plasmalemma and the secretory granule membrane, are clearly distinguishable in freeze-fracture because of their different densities in particles. In order to obtain point-specific information about the fusion-fission of these two membranes that occurs during the secretory cycle, glands were studied at various times (5 min to 6 h) after stimulation with isoproterenol. We observed that… CONTINUE READING