Dynamic changes of GAD65 autoantibody epitope specificities in individuals at risk of developing type 1 diabetes

@article{Schlosser2005DynamicCO,
  title={Dynamic changes of GAD65 autoantibody epitope specificities in individuals at risk of developing type 1 diabetes},
  author={Michael Schlosser and J. P. Banga and A. M. Madec and Katherine A Binder and Martina Strebelow and Ilona Rjasanowski and Ralf Wassmuth and Lisa K. Gilliam and Dong Luo and Christiane S. Hampe},
  journal={Diabetologia},
  year={2005},
  volume={48},
  pages={922-930}
}
Progression to type 1 diabetes is associated with intramolecular epitope spreading to disease-specific antibody epitopes located in the middle region of glutamic acid decarboxylase 65 (GAD65). The relationship between intramolecular epitope spreading of autoantibodies specific to GAD65 in relation to the risk of developing type 1 diabetes was tested in 22… CONTINUE READING