Dynamic changes in the expression of MicroRNA-31 during inflammatory bowel disease-associated neoplastic transformation.

@article{Olaru2011DynamicCI,
  title={Dynamic changes in the expression of MicroRNA-31 during inflammatory bowel disease-associated neoplastic transformation.},
  author={Alexandru V. Olaru and Florin M. Selaru and Yuriko Mori and Christine Vazquez and Stefan David and Bogdan C. Paun and Yulan Cheng and Zhe Jin and Jian Yang and Rachana Agarwal and John M. Abraham and Themistocles Dassopoulos and Mary Louise Harris and Theodore M. Bayless and John H. Kwon and Noam H Harpaz and Ferenc Liv{\'a}k and Stephen J. Meltzer},
  journal={Inflammatory bowel diseases},
  year={2011},
  volume={17 1},
  pages={
          221-31
        }
}
BACKGROUND Patients with inflammatory bowel disease (IBD) are at increased risk of developing colorectal cancer. Aberrant microRNA (miR) expression has been linked to carcinogenesis; however, no reports document a relationship between IBD-related neoplasia (IBDN) and altered miR expression. In the current study we sought to identify specific miR dysregulation along the normal-inflammation-cancer axis. METHODS miR microarrays and quantitative reverse-transcriptase polymerase chain reaction (RT… CONTINUE READING

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