Dynamic changes in fat oxidation in human primary myocytes mirror metabolic characteristics of the donor.

Abstract

Metabolic flexibility of skeletal muscle, that is, the preference for fat oxidation (FOx) during fasting and for carbohydrate oxidation in response to insulin, is decreased during insulin resistance. The aim of this study was to test the hypothesis that the capacity of myotubes to oxidize fat in vitro reflects the donor's metabolic characteristics. Insulin… (More)

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@article{Ukropcov2005DynamicCI, title={Dynamic changes in fat oxidation in human primary myocytes mirror metabolic characteristics of the donor.}, author={Barbara Ukropcov{\'a} and Michele McNeil and Olga R. Sereda and Lilian de Jonge and Hui Xie and George A. Bray and Steven Rathgeb Smith}, journal={The Journal of clinical investigation}, year={2005}, volume={115 7}, pages={1934-41} }