Dynamic changes in Histone H3 lysine 9 acetylation localization patterns during neuronal maturation require MeCP2.

@article{Thatcher2006DynamicCI,
  title={Dynamic changes in Histone H3 lysine 9 acetylation localization patterns during neuronal maturation require MeCP2.},
  author={Karen N Thatcher and Janine M LaSalle},
  journal={Epigenetics},
  year={2006},
  volume={1 1},
  pages={24-31}
}
Mutations within the gene encoding methyl CpG binding protein 2 (MECP2) cause the autism-spectrum neurodevelopmental disorder Rett Syndrome (RTT). MECP2 recruits histone deacetylase to methylated DNA and acts as a long-range regulator of methylated genes. Despite ubiquitous MECP2 expression, the phenotype of RTT and the Mecp2-deficient mouse is largely… CONTINUE READING