Dynamic analysis of Arabidopsis AP2 σ subunit reveals a key role in clathrin-mediated endocytosis and plant development.

@article{Fan2013DynamicAO,
  title={Dynamic analysis of Arabidopsis AP2 σ subunit reveals a key role in clathrin-mediated endocytosis and plant development.},
  author={Lusheng Fan and Huaiqing Hao and Yiqun Xue and Liang Zhang and Kai Song and Zhaojun Ding and Miguel A Botella and Haiyang Wang and Jinxing Lin},
  journal={Development},
  year={2013},
  volume={140 18},
  pages={3826-37}
}
Clathrin-mediated endocytosis, which depends on the AP2 complex, plays an essential role in many cellular and developmental processes in mammalian cells. However, the function of the AP2 complex in plants remains largely unexplored. Here, we show in Arabidopsis that the AP2 σ subunit mutant (ap2 σ) displays various developmental defects that are similar to those of mutants defective in auxin transport and/or signaling, including single, trumpet-shaped and triple cotyledons, impaired vascular… CONTINUE READING
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