Dynamic activation of the anterior cingulate cortex during anticipatory anxiety

@article{Straube2009DynamicAO,
  title={Dynamic activation of the anterior cingulate cortex during anticipatory anxiety},
  author={Thomas Straube and Stephanie Schmidt and Thomas Weiss and Hans-Joachim Mentzel and Wolfgang H. R. Miltner},
  journal={NeuroImage},
  year={2009},
  volume={44},
  pages={975-981}
}
Based on theoretical models, we investigated the dynamics of brain activation during anticipatory anxiety using functional magnetic resonance imaging and a combined parametric/correlational design. Subjects (16 females) anticipated the application of electrical shocks of varying intensity resulting in four different threat levels. The parametric analysis revealed an inverted U-function of activation in the ventral anterior cingulate cortex (ACC) depending on the level of threat. Furthermore… CONTINUE READING

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