Dynamic SPECT imaging of dopamine D2 receptors in human subjects with iodine-123-IBZM.

Abstract

We studied the uptake, distribution, metabolism and washout of the dopamine D2 receptor ligand [123I]IBZM in healthy subjects (n = 12) with dynamic brain SPECT. The highest radioactivity level was detected in the striatum. Operationally-defined striatal "specific" uptake peaked at 69 min postinjection of radioligand and showed a gradual decline of 15% per… (More)

Topics

  • Presentations referencing similar topics