Dynamic Roles of microRNAs in Neurogenesis

  title={Dynamic Roles of microRNAs in Neurogenesis},
  author={M Lang and Yan-hong Shi},
  booktitle={Front. Neurosci.},
MicroRNAs (miRNAs) are short non-coding RNAs that regulate gene expression at the post-transcriptional level by mediating mRNA degradation or translational inhibition. MiRNAs are implicated in many biological functions, including neurogenesis. It has been shown that miRNAs regulate multiple steps of neurogenesis, from neural stem cell proliferation to neuronal differentiation and maturation. MiRNAs execute their functions in a dynamic and context-dependent manner by targeting diverse downstream… CONTINUE READING