Dynamic Organization of Aminoacyl-tRNA Synthetase Complexes in the Cytoplasm of Human Cells.

@article{Kamiska2009DynamicOO,
  title={Dynamic Organization of Aminoacyl-tRNA Synthetase Complexes in the Cytoplasm of Human Cells.},
  author={Monika Kamińska and Svitlana Havrylenko and Paulette Decottignies and Pierre Le Mar{\'e}chal and Boris Negrutskii and Marc Mirande},
  journal={The Journal of biological chemistry},
  year={2009},
  volume={284 20},
  pages={13746-54}
}
The localization in space and in time of proteins within the cytoplasm of eukaryotic cells is a central question of the cellular compartmentalization of metabolic pathways. The assembly of proteins within stable or transient complexes plays an essential role in this process. Here, we examined the subcellular localization of the multi-aminoacyl-tRNA synthetase complex in human cells. The sequestration of its components within the cytoplasm rests on the presence of the eukaryotic-specific… CONTINUE READING

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Compartmentalization of Translation 13754 JOURNAL OF BIOLOGICAL CHEMISTRY

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