Dynamic O-(2-[18F]fluoroethyl)-L-tyrosine (F-18 FET) PET for glioma grading: assessment of individual probability of malignancy.

@article{Calcagni2011DynamicO,
  title={Dynamic O-(2-[18F]fluoroethyl)-L-tyrosine (F-18 FET) PET for glioma grading: assessment of individual probability of malignancy.},
  author={Maria Lucia Calcagni and Guido Galli and Alessandro Giordano and Silvia Taralli and Carmelo Anile and Andreas Niesen and Richard Paul Baum},
  journal={Clinical nuclear medicine},
  year={2011},
  volume={36 10},
  pages={841-7}
}
PURPOSE (1) To investigate the diagnostic value of some O-(2-[F]fluoroethyl)-L-tyrosine (F-18 FET) indices derived from the dynamic acquisition to differentiate low-grade gliomas from high-grade; (2) to analyze the course of tumor time-activity curves (TACs); and (3) to calculate the individual probability of a high-grade glioma using the logistic regression. METHODS Seventeen low-grade (WHO I-II) and 15 high-grade (WHO III-IV) gliomas were studied with dynamic F-18 FET PET. Regions of… CONTINUE READING
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