Dynamic Growth and Shrinkage Govern the pH Dependence of RecA Filament Stability

Abstract

RecA proteins form a long stable filament on a single-stranded DNA and catalyze strand exchange reaction. The stability of RecA filament changes dramatically with pH, yet its detailed mechanism is not known. Here, using a single molecule assay, we determined the binding and dissociation rates of RecA monomers at the filament ends at various pH. The pH… (More)
DOI: 10.1371/journal.pone.0115611

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Cite this paper

@inproceedings{Kim2015DynamicGA, title={Dynamic Growth and Shrinkage Govern the pH Dependence of RecA Filament Stability}, author={Sung Hyun Kim and Jeehae Park and Chirlmin Joo and Doseok Kim and Taekjip Ha}, booktitle={PloS one}, year={2015} }