Dynamic DNA-toolbox reaction circuits: a walkthrough.

@article{Baccouche2014DynamicDR,
  title={Dynamic DNA-toolbox reaction circuits: a walkthrough.},
  author={Alexandre Baccouche and Kevin Montagne and Adrien Padirac and Teruo Fujii and Yannick Rondelez},
  journal={Methods},
  year={2014},
  volume={67 2},
  pages={
          234-49
        }
}
In living organisms, the integration of signals from the environment and the molecular computing leading to a cellular response are orchestrated by Gene Regulatory Networks (GRN). However, the molecular complexity of in vivo genetic regulation makes it next to impossible to describe in a quantitative manner. Reproducing, in vitro, reaction networks that could mimic the architecture and behavior of in vivo networks, yet lend themselves to mathematical modeling, represents a useful strategy to… CONTINUE READING

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