Dynactin Enhances the Processivity of Kinesin‐2

@article{Berezuk2007DynactinET,
  title={Dynactin Enhances the Processivity of Kinesin‐2},
  author={Matthew A Berezuk and Trina A. Schroer},
  journal={Traffic},
  year={2007},
  volume={8}
}
Kinesin‐2 is a major microtubule‐based motor in most cell types. Its in vitro motile properties have been analyzed extensively and been found to differ considerably from kinesin‐1. Although recombinant kinesin‐2 heterodimers exhibit processive movement, the processivity of the native kinesin‐2 holoenzyme has never been evaluated. Kinesin‐2 can interact with dynactin, a ‘processivity factor’ for cytoplasmic dynein, which may alter its motile properties. In this study, we analyze the in vitro… 

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...

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