Dying woolly mammoths were in ‘genetic meltdown’

@article{Switek2017DyingWM,
  title={Dying woolly mammoths were in ‘genetic meltdown’},
  author={Brian Switek},
  journal={Nature},
  year={2017}
}
Genomic study of extinction in progress may give insights into modern conservation. 
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References

Excess of genomic defects in a woolly mammoth on Wrangel island
TLDR
This work identifies deletions, retrogenes, and non-functionalizing point mutations in woolly mammoths from an isolated population on Wrangel island where mammoths subsisted with small effective population size more than 43-fold lower than previous populations.