Dye-sensitized photo-oxidation of enzymes.

  title={Dye-sensitized photo-oxidation of enzymes.},
  author={Ching Sung Tsai and Jon Godin and A Joshua Wand},
  journal={The Biochemical journal},
  volume={225 1},
Heart lipoamide dehydrogenase, liver alcohol dehydrogenase and egg-white lysozyme are photo-oxidized in the presence of various dye sensitizers. The photodynamic process is preceded by the binding between the enzyme and the sensitizers. Among the commonly used dyes, halogenated xanthines and thiazine are effective sensitizers for the photo-inactivation of these three enzymes. Histidine residues are the primary target for the sensitized photo-oxidation that inactivates lipoamide dehydrogenase… CONTINUE READING

Similar Papers

Loading similar papers…