Dye lipophilicity and retention in lipid membranes: implications for single-molecule spectroscopy.

Abstract

Fluorescence studies of individual lipid vesicles rely on the proper positioning of probes in the lipid milieu. This is true for both positional tags and chemoselective fluorogenic probes that undergo chemical modification following reaction with an analyte of interest within the lipid environment. The present report describes lipophilicity and localization… (More)
DOI: 10.1021/la5021669

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