DvD: An R/Cytoscape pipeline for drug repurposing using public repositories of gene expression data

@inproceedings{Pacini2013DvDAR,
  title={DvD: An R/Cytoscape pipeline for drug repurposing using public repositories
of gene expression data},
  author={Clare Pacini and Francesco Iorio and Emanuel J. V. Gonçalves and Murat Iskar and Thomas Klabunde and Peer Bork and Julio Saez-Rodriguez},
  booktitle={Bioinformatics},
  year={2013}
}
SUMMARY Drug versus Disease (DvD) provides a pipeline, available through R or Cytoscape, for the comparison of drug and disease gene expression profiles from public microarray repositories. Negatively correlated profiles can be used to generate hypotheses of drug-repurposing, whereas positively correlated profiles may be used to infer side effects of drugs. DvD allows users to compare drug and disease signatures with dynamic access to databases Array Express, Gene Expression Omnibus and data… CONTINUE READING
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