Dusty protein kinases: primary structure, gene evolution, tissue specific expression and unique features of the catalytic domain.

@article{Peng2006DustyPK,
  title={Dusty protein kinases: primary structure, gene evolution, tissue specific expression and unique features of the catalytic domain.},
  author={Jianbin Peng and Wenji Dong and Yin Chen and Rong Qing Mo and Jan-fang Cheng and Chi-Chung Hui and Narla Mohandas and Cheng-Han Huang},
  journal={Biochimica et biophysica acta},
  year={2006},
  volume={1759 11-12},
  pages={562-72}
}
Ser/Thr- and Tyr-Protein kinases constitute a key switch underlying the dynamic nature and graded regulation of signal transduction and pathway activities in cellular organization. Here we describe the identification and characterization of Dusty, a single-copy gene that arose in metazoan evolution and encodes a putative dual Ser/Thr and Tyr protein kinase… CONTINUE READING