During multicellular migration, myosin ii serves a structural role independent of its motor function.

@article{Xu2001DuringMM,
  title={During multicellular migration, myosin ii serves a structural role independent of its motor function.},
  author={X. Z. Shawn Xu and Ethan Lee and Taiping Chen and Edward R. Kuczmarski and Rex L. Chisholm and David A. Knecht},
  journal={Developmental biology},
  year={2001},
  volume={232 1},
  pages={255-64}
}
We have shown previously that cells lacking myosin II are impaired in multicellular motility. We now extend these results by determining whether myosin contractile function is necessary for normal multicellular motility and shape control. Myosin from mutants lacking the essential (mlcE(-)) myosin light chain retains the ability to form bipolar filaments that bind actin, but shows no measurable in vitro or in vivo contractile function. The contractile function is necessary for cell shape control… CONTINUE READING