During fetal muscle development, clones of cells contribute to both primary and secondary fibers.

@article{Evans1994DuringFM,
  title={During fetal muscle development, clones of cells contribute to both primary and secondary fibers.},
  author={Dawna Evans and Helen Baillie and A G Caswell and Peter Wigmore},
  journal={Developmental biology},
  year={1994},
  volume={162 2},
  pages={348-53}
}
All mammalian muscle fibers are formed by cell fusion, but fiber formation occurs in two successive waves. Initially a small number of large fibers (primaries) are produced and are used as a scaffold for the formation of a larger number of smaller later forming fibers (secondaries). It has been reported that different populations of myoblasts are present at different ages, but it is unclear whether separate populations of cells contribute to primary and secondary fibers during the period of… CONTINUE READING

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