Duration of untreated psychosis and negative symptoms--a systematic review and meta-analysis of individual patient data.

@article{Boonstra2012DurationOU,
  title={Duration of untreated psychosis and negative symptoms--a systematic review and meta-analysis of individual patient data.},
  author={Nynke Boonstra and Rianne M. C. Klaassen and Sjoerd Sytema and Max Marshall and L D Dick de Haan and Lex Wunderink and Durk Wiersma},
  journal={Schizophrenia research},
  year={2012},
  volume={142 1-3},
  pages={12-9}
}
BACKGROUND Longer duration of untreated psychosis (DUP) is associated with poorer outcome in terms of positive symptoms, relapse rate, and time to remission. In contrast, the association with negative symptoms is less consistent. AIMS The study had three aims. First, to arrive at a more precise estimate of the correlation between DUP and negative symptoms… CONTINUE READING