Duration of fusion pore opening and the amount of hormone released are regulated by myosin II during kiss-and-run exocytosis.

@article{Aoki2010DurationOF,
  title={Duration of fusion pore opening and the amount of hormone released are regulated by myosin II during kiss-and-run exocytosis.},
  author={Ryo Aoki and Tetsuya Kitaguchi and Manami Oya and Yuki Yanagihara and Mai Sato and Atsushi Miyawaki and Takashi Tsuboi},
  journal={The Biochemical journal},
  year={2010},
  volume={429 3},
  pages={
          497-504
        }
}
Since the fusion pore of the secretory vesicle is resealed before complete dilation during 'kiss-and-run' exocytosis, their cargoes are not completely released. Although the transient fusion pore is kept open for several seconds, the precise mechanisms that control fusion pore maintenance, and their physiological significance, are not well understood. Using dual-colour TIRF (total internal reflection fluorescence) microscopy in neuroendocrine PC12 cells, we show that myosin II regulates the… 
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