Duration of Immunity Against Pertussis After Natural Infection or Vaccination

  title={Duration of Immunity Against Pertussis After Natural Infection or Vaccination},
  author={A. Wendelboe and A. van Rie and S. Salmaso and J. Englund},
  journal={The Pediatric Infectious Disease Journal},
  • A. Wendelboe, A. van Rie, +1 author J. Englund
  • Published 2005
  • Medicine
  • The Pediatric Infectious Disease Journal
  • Despite decades of high vaccination coverage, pertussis has remained endemic and reemerged as a public health problem in many countries in the past 2 decades. Waning of vaccine-induced immunity has been cited as one of the reasons for the observed epidemiologic trend. A review of the published data on duration of immunity reveals estimates that infection-acquired immunity against pertussis disease wanes after 4–20 years and protective immunity after vaccination wanes after 4–12 years. Further… CONTINUE READING
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