Duration Control of Protein Expression in Vivo by Light-Mediated Reversible Activation of Translation.

Abstract

The photocontrol of protein expression enables the spatiotemporal induction of biological events in living cells or organisms. However, commonly used method such as photocontrollable transcription factor or caged nucleic acids is unsuitable for precise control of the duration of protein expression. Here, I report a photocontrollable cap (PC-cap) that can… (More)
DOI: 10.1021/acschembio.6b00684

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