Dural substitute for long-term imaging of cortical activity in behaving monkeys and its clinical implications.

  title={Dural substitute for long-term imaging of cortical activity in behaving monkeys and its clinical implications.},
  author={Amos Arieli and Amiram Grinvald and Hamutal Slovin},
  journal={Journal of neuroscience methods},
  volume={114 2},
We present a transparent silicone dural substitute, which we have been using for the last 7 years for imaging cortical dynamics in awake behaving monkeys. This substitute enabled us to record optically for more than a year intrinsic or voltage sensitive dye signals. It is thin and elastic enough to allow microelectrode to pass through without any damage, using full visual control to target the electrode to the desirable recording site. This implant has proved crucial for maintaining the cortex… CONTINUE READING


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