Dupuytren’s disease and the risk of malignant neoplasms

  title={Dupuytren’s disease and the risk of malignant neoplasms},
  author={Andrzej Ż Żyluk and Katarzyna Paszkowska-Szczur and Satish Gupta and Rodney J. Scott and Jan Lubiński and Tadeusz Dębniak},
  booktitle={Hereditary cancer in clinical practice},
The object of this study was the investigation of the risk of occurrence of malignant neoplasms in 508 patients with Dupuytren's disease (DD) and in 2157 of their 1st degree relatives. In the first stage of the study, we evaluated the tumour spectrum as well as the age of the patient at diagnosis of cancers in DD families along with the observed and expected frequencies of malignancies. In the second stage of the study, we examined the distribution of 20 common mutations/polymorphisms in 12… CONTINUE READING
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