Duplication of enhancer sequences in human papillomavirus 6 from condylomas of the mamilla.

@article{Kulke1989DuplicationOE,
  title={Duplication of enhancer sequences in human papillomavirus 6 from condylomas of the mamilla.},
  author={Reinhard Kulke and Gerd E. Gross and Herbert Pfister},
  journal={Virology},
  year={1989},
  volume={173 1},
  pages={
          284-90
        }
}
Human papillomavirus (HPV) 6 usually induces tumors of the genital, oral, or laryngeal mucosa. An HPV 6-related DNA of 8.2 kb was detected in an extrachromosomal state in atypically located condylomas of the mamilla and was molecularly cloned. The identity of the cloned HPV DNA and the viral DNA in the biopsy was confirmed by comparative Pstl cleavage analysis, which showed typical HPV 6 DNA fragment patterns except for 0.2-kb larger B fragments. Sequencing revealed an exact 236-bp duplication… CONTINUE READING
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