Duplication of 8p23.1: a cytogenetic anomaly with no established clinical significance.

@article{Barber1998DuplicationO8,
  title={Duplication of 8p23.1: a cytogenetic anomaly with no established clinical significance.},
  author={John C K Barber and Christine A Joyce and Morag N. Collinson and James Clair Nicholson and Lionel R Willatt and Harold M. Dyson and Michelle Bateman and Andrew J. Green and John R. W. Yates and Nicholas R. Dennis},
  journal={Journal of medical genetics},
  year={1998},
  volume={35 6},
  pages={
          491-6
        }
}
We present seven families with a cytogenetic duplication of the short arm of chromosome 8 at band 8p23.1. The duplication has been transmitted from parents to offspring in four of the seven families. In three families, the source of the extra material and its euchromatic origin were established using FISH with a YAC which was mapped to 8p23.1 and a whole chromosome paint for chromosome 8. FISH signals from this YAC were significantly larger on the duplicated chromosome compared with the normal… CONTINUE READING

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