Duplication and remoulding of tRNA genes during the evolutionary rearrangement of mitochondrial genomes

@article{Cantatore1987DuplicationAR,
  title={Duplication and remoulding of tRNA genes during the evolutionary rearrangement of mitochondrial genomes},
  author={Palmiro Cantatore and Maria Nicola Gadaleta and Marina Roberti and Cecilia Saccone and A. C. Wilson},
  journal={Nature},
  year={1987},
  volume={329},
  pages={853-855}
}
During the evolution of sea urchins, a transfer RNA gene lost its tRNA function and became part of a protein-coding gene. This functional loss of a tRNA with specificity for one group of leucine codons (CUN, where N is any base) was accompanied by the gain of a new tRNA with that specificity. The new tRNA gene for CUN codons appears to have evolved by duplication and divergence from a tRNA gene specific for another group of leucine codons (UUR, where R is a purine). These proposals account for… CONTINUE READING

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