Duplication and Functional Specialization of the Telomere-capping Protein Cdc13 in Candida Species*

@article{Lue2013DuplicationAF,
  title={Duplication and Functional Specialization of the Telomere-capping Protein Cdc13 in Candida Species*},
  author={Neal F. Lue and Jamie M. Chan},
  journal={The Journal of Biological Chemistry},
  year={2013},
  volume={288},
  pages={29115 - 29123}
}
Background: Cdc13 in Candida species is small and missing conserved domains. Results: A second Cdc13 homologue (Cdc13B) was shown to form heterodimers with Cdc13 and to mediate overlapping functions in telomere protection. Conclusion: Cdc13 has undergone duplication and functional specialization in a branch of Saccharomycotina yeast. Significance: Understanding the assembly and mechanisms of fungal CST complex provides insights on the evolution and function of this crucial telomere complex. The… 

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