Duplicated gelsolin family genes in zebrafish: a novel scinderin-like gene (scinla) encodes the major corneal crystallin.

@article{Jia2007DuplicatedGF,
  title={Duplicated gelsolin family genes in zebrafish: a novel scinderin-like gene (scinla) encodes the major corneal crystallin.},
  author={Sujuan Jia and Marina V. Omelchenko and Donita Garland and Vasilis Vasiliou and Jyotshnabala Kanungo and Michael Y Spencer and Yuri I. Wolf and Eugene V. Koonin and Joram Piatigorsky},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={2007},
  volume={21 12},
  pages={
          3318-28
        }
}
We have previously identified a gelsolin-like protein (C/L-gelsolin) as a corneal crystallin in zebrafish. Here we show by phylogenetic analysis that there are at least six genes encoding gelsolin-like proteins based on their gelsolin domains in zebrafish: gsna and gsnb group with the vertebrate gelsolin gene, scina and scinb group with the scinderin (adseverin) gene, and scinla (C/L-gelsolin) and scinlb are novel scinderin-like genes. RT-PCR showed that scinla, scinlb, and gsnb are… CONTINUE READING
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Promoter/enhancer analysis of the zebrafish gelsolin-like 1 (gsn1) gene for the cornea specific expression [ARVO abstract

  • S. Yoshikawa, E. G. Norcom, R. W. Yee, X. C. Zhao
  • Invest. Ophthalmol. Vis Sci
  • 2006
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