Dupilumab: a milestone in the treatment of atopic dermatitis

  title={Dupilumab: a milestone in the treatment of atopic dermatitis},
  author={A. Tsianakas and S. St{\"a}nder},
  journal={The Lancet},
  • A. Tsianakas, S. Ständer
  • Published 2016
  • Medicine
  • The Lancet
  • Atopic dermatitis is the most common chronic infl ammatory, pruritic skin disease with a high prevalence, both in adults (2–10%) and children (15–30%). From a scientifi c viewpoint, atopic dermatitis can be attributed to both a genetically mediated epidermal barrier dysfunction and Th2-driven infl ammation. Therefore, classic treatment regimens, such as emollients, topical steroids, and calcineurin inhibitors, are still regarded as viable. For severe cases, systemic use of the immunosuppressant… CONTINUE READING
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