Duodenal sensory neurons project to sphincter of Oddi ganglia in guinea pig.

  title={Duodenal sensory neurons project to sphincter of Oddi ganglia in guinea pig.},
  author={Audra L Kennedy and G M Mawe},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  volume={18 19},
Retrograde labeling of duodenum-sphincter of Oddi (SO) preparations in vitro with the carbocyanine dye DiI revealed that duodenal neurons project to the SO. The duodenum-SO-projecting neurons were immunoreactive (IR) for choline acetyltransferase but not nitric oxide synthase or calretinin, indicating that this is a cholinergic projection and that this pathway is distinct from the circuitry involved in the ascending limb of the peristaltic reflex. Approximately 20% of the duodenum-SO projection… CONTINUE READING


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