Dumbbell-PCR: a method to quantify specific small RNA variants with a single nucleotide resolution at terminal sequences

Abstract

Recent advances in next-generation sequencing technologies have revealed that cellular functional RNAs are not always expressed as single entities with fixed terminal sequences but as multiple isoforms bearing complex heterogeneity in both length and terminal sequences, such as isomiRs, the isoforms of microRNAs. Unraveling the biogenesis and biological… (More)
DOI: 10.1093/nar/gkv218

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@inproceedings{Honda2015DumbbellPCRAM, title={Dumbbell-PCR: a method to quantify specific small RNA variants with a single nucleotide resolution at terminal sequences}, author={Shozo Honda and Yohei Kirino}, booktitle={Nucleic acids research}, year={2015} }