Duloxetine vs. placebo in patients with painful diabetic neuropathy

@article{Goldstein2005DuloxetineVP,
  title={Duloxetine vs. placebo in patients with painful diabetic neuropathy},
  author={D. Goldstein and Y. Lu and M. Detke and T. Lee and S. Iyengar},
  journal={Pain},
  year={2005},
  volume={116},
  pages={109-118}
}
&NA; The aim of this study was to examine the efficacy and safety of duloxetine, a balanced and potent dual reuptake inhibitor of serotonin and norepinephrine, in the management of diabetic peripheral neuropathic pain. Serotonin and norepinephrine are thought to inhibit pain via descending pain pathways. In a 12‐week, multicenter, double‐blind study, 457 patients experiencing pain due to polyneuropathy caused by Type 1 or Type 2 diabetes mellitus were randomly assigned to treatment with… Expand
739 Citations

Paper Mentions

Interventional Clinical Trial
The objective and the purpose of the trial is to: assess the efficacy of Pregabalin Krka and Dulsevia® in patients with PDPN, investigate the effect of Pregabalin Krka and Dulsevia® on… Expand
ConditionsPainful Diabetic Peripheral Neuropathy
InterventionDrug
Interventional Clinical Trial
Diabetic neuropathy is a progressive complication causing serious problems in 25-40% of diabetic patients. Anecdotal reports have indicated improvement with pulsatile IV insulin… Expand
ConditionsDiabetic Neuropathy
InterventionProcedure
Interventional Clinical Trial
Diabetic neuropathy is a progressive complication causing serious problems in 25-40% of diabetic patients. Anecdotal reports have indicated improvement with pulsatile IV insulin in… Expand
ConditionsDiabetes Mellitus, With Complications
InterventionProcedure
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References

SHOWING 1-10 OF 31 REFERENCES
Duloxetine 60 mg once daily dosing versus placebo in the acute treatment of major depression.
  • 277
Duloxetine, 60 mg once daily, for major depressive disorder: a randomized double-blind placebo-controlled trial.
  • 391
A systematic review of antidepressants in neuropathic pain
  • 904
Duloxetine in the treatment of major depressive disorder
  • D. Goldstein
  • Medicine
  • Neuropsychiatric disease and treatment
  • 2007
  • 161
  • Highly Influential
Efficacy of pharmacological treatments of neuropathic pain: an update and effect related to mechanism of drug action
  • 1,106
Efficacy of Duloxetine, a Potent and Balanced Serotonin-Norepinephrine Reuptake Inhibitor in Persistent Pain Models in Rats
  • 265
  • PDF
Dual serotonin and noradrenaline uptake inhibitor class of antidepressants potential for greater efficacy or just hype?
  • D. Wong, F. Bymaster
  • Medicine
  • Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques
  • 2002
  • 108
Pain assessment: global use of the Brief Pain Inventory.
  • 3,617
Textbook of pain
  • 3,247
The short-form McGill pain questionnaire
  • 3,529
  • PDF
...
1
2
3
4
...