Duloxetine in acute major depression: review of comparisons to placebo and standard antidepressants using dissimilar methods.

@article{Girardi2009DuloxetineIA,
  title={Duloxetine in acute major depression: review of comparisons to placebo and standard antidepressants using dissimilar methods.},
  author={Paolo Girardi and Maurizio Pompili and Marco Innamorati and Michele Mancini and Gianluca Serafini and Lorenzo Mazzarini and Antonio Del Casale and Roberto Tatarelli and Ross J. Baldessarini},
  journal={Human psychopharmacology},
  year={2009},
  volume={24 3},
  pages={177-90}
}
BACKGROUND Randomized controlled trials (RCTs) of duloxetine (DLX), an inhibitor of both norepinephrine and serotonin transporters (SNRI), have tested its efficacy in acute major depressive disorder (MDD) versus placebo (PBO) or standard serotonin-reuptake inhibitors (SRIs) and require review, comparing analytical methods. METHOD Computerized searching to identify reports of RCTs of DLX in adult, acute MDD patients permitted meta-analytic pooling to estimate overall response and remission… CONTINUE READING

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Duloxetine in acute major depression : review of comparisons to placebo and standard antidepressants using dissimilar methods .
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