Duloxetine and pregabalin: safe and effective for the long-term treatment of fibromyalgia?


This Practice Point commentary discusses the first two trials of long-term drug treatment in fibromyalgia. In Russell et al.'s study, 33% of patients receiving 6-month treatment with 60 mg/day duloxetine responded to therapy; the number needed to treat was seven. In the three treatment arms, 15% (60 mg/day duloxetine), 27% (120 mg/day duloxetine) and 13… (More)
DOI: 10.1038/ncpneuro0936